| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 1978 | 12/2 | St. Xavier | 21 | 42 | L | 1 | Neutral | Louisville | Fairgrounds Stadium | Roy Walton | championship at Louisville (state) | ||||
| 2012 | 11/2 | St. Xavier | 13 | 66 | L | 1 | Away | Louisville | Mike Harmon | playoff at Louisville | |||||
| 34 | 108 | 0 | 2 | 0 | .000 | ||||||||||
| 17.00 | 54.00 | -37.00 | |||||||||||||