| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 2017 | 9/22 | Louisville DeSales | 26 | 38 | L | 1 | Home | Lexington | Joseph K. Ford Stadium | Mark Perry | |||||
| 2018 | 9/21 | Louisville DeSales | 24 | 38 | L | 1 | Away | Louisville | Nigel Smith | ||||||
| 2019 | 9/13 | Louisville DeSales | 34 | 31 | W | 1 | Home | Lexington | Joseph K. Ford Stadium | Nigel Smith | |||||
| 84 | 107 | 1 | 2 | 0 | .333 | ||||||||||
| 28.00 | 35.67 | -7.67 | |||||||||||||