| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Place | Location | Field | Coach | Notes |
| 1960 | 10/15 | Bowling Green | 26 | 13 | W | 1 | Away | Bowling Green | Western Stadium | Homer Rice | ||||
| 1961 | 10/13 | Bowling Green | 49 | 6 | W | 1 | Home | Fort Thomas | David Cecil Memorial Stadium | Homer Rice | ||||
| 1995 | 12/1 | Bowling Green | 12 | 28 | L | 1 | Neutral | Louisville | Cardinal Stadium | Dale Mueller | championship at Louisville | |||
| 2007 | 12/7 | Bowling Green | 28 | 7 | W | 1 | Neutral | Louisville | Cardinal Stadium | Dale Mueller | championship at Louisville | |||
| 2021 | 8/21 | Bowling Green | 21 | 18 | W | 1 | Neutral | Bowling Green | WKU | Robert Sphire | ||||
| 136 | 72 | 4 | 1 | 0 | .800 | |||||||||
| 27.20 | 14.40 | 12.80 | ||||||||||||