| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes |
| 2009 | 9/4 | Notre Dame, OH | 29 | 25 | W | 1 | Home | Greenup | Mike Copley | |||||
| 2010 | 9/4 | Notre Dame, OH | 28 | 7 | W | 1 | Away | Portsmouth | Spartan Municipal Stadium | Mike Copley | ||||
| 2019 | 9/27 | Notre Dame, OH | 45 | 0 | W | 1 | Away | Portsmouth | Spartan Municipal Stadium | Scott Grizzle | ||||
| 102 | 32 | 3 | 0 | 0 | 1.000 | |||||||||
| 34.00 | 10.67 | 23.33 |