| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Place | Location | Field | Coach | Notes |
| 1975 | 11/11 | Franklin County | 7 | 0 | W | 1 | Away | Frankfort | Don Danko | playoff at Frankfort | ||||
| 1975 | 11/15 | North Hardin | 10 | 0 | W | 1 | Away | Radcliff | Don Danko | playoff at Radcliff | ||||
| 1975 | 11/21 | Tilghman | 3 | 36 | L | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1979 | 11/2 | Henry Clay | 0 | 16 | L | 1 | Away | Lexington | Heber Field | Don Danko | playoff at Lexington | |||
| 1982 | 11/5 | Bryan Station | 4 | 21 | L | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1983 | 11/4 | Tates Creek | 16 | 12 | W | 1 | Away | Lexington | Don Danko | playoff at Lexington | ||||
| 1983 | 11/11 | Boone County | 27 | 28 | L | 1 | 1OT | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | ||
| 1985 | 11/1 | Laurel County | 12 | 13 | L | 1 | Away | London | Don Danko | playoff at London | ||||
| 1986 | 11/7 | Tates Creek | 21 | 18 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1986 | 11/14 | Boone County | 0 | 27 | L | 1 | Away | Florence | Irv Goode Field | Don Danko | playoff at Florence | |||
| 1987 | 11/6 | Boone County | 0 | 40 | L | 1 | Away | Florence | Irv Goode Field | Don Danko | playoff at Florence | |||
| 1991 | 11/8 | Paul Laurence Dunbar | 53 | 8 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1991 | 11/15 | Boone County | 28 | 7 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1991 | 11/22 | Madison Central | 41 | 13 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1991 | 11/29 | Trinity | 28 | 20 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1991 | 12/7 | St. Xavier | 28 | 21 | W | 1 | Neutral | Louisville | Cardinal Stadium | Don Danko | championship at Louisville | |||
| 1992 | 11/6 | Campbell County | 27 | 26 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1992 | 11/13 | Boone County | 7 | 20 | L | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1993 | 11/5 | Campbell County | 20 | 14 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1993 | 11/12 | Boone County | 0 | 43 | L | 1 | Away | Florence | Irv Goode Field | Don Danko | playoff at Florence | |||
| 1994 | 11/4 | Boone County | 20 | 35 | L | 1 | Away | Florence | Irv Goode Field | Don Danko | playoff at Florence | |||
| 1995 | 11/3 | North Laurel | 30 | 8 | W | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1995 | 11/10 | Henry Clay | 14 | 19 | L | 1 | Home | Winchester | Cardinal Stadium | Don Danko | playoff at Winchester | |||
| 1996 | 11/8 | Paul Laurence Dunbar | 21 | 28 | L | 1 | Away | Lexington | Don Danko | playoff at Lexington | ||||
| 1999 | 11/5 | South Laurel | 2 | 55 | L | 1 | Away | London | Gilliam Stadium | Paul Columbia | playoff at London | |||
| 2000 | 11/3 | Johnson County | 7 | 35 | L | 1 | Away | Paintsville | Eagle Stadium | Paul Columbia | playoff at Paintsville | |||
| 2002 | 10/8 | Woodford County | 27 | 51 | L | 1 | Away | Versailles | Community Stadium | Paul Columbia | playoff at Versailles | |||
| 2003 | 11/7 | Paul Laurence Dunbar | 3 | 42 | L | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2004 | 11/5 | Henry Clay | 35 | 48 | L | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2005 | 11/4 | Paul Laurence Dunbar | 26 | 30 | L | 1 | Away | Lexington | Jon R. Akers Stadium | Paul Columbia | playoff at Lexington | |||
| 2006 | 11/3 | Montgomery County | 28 | 24 | W | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2006 | 11/17 | Henry Clay | 7 | 21 | L | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2007 | 11/9 | Madison Central | 14 | 27 | L | 1 | Away | Richmond | Paul Columbia | playoff at Richmond | ||||
| 2008 | 11/14 | Fern Creek | 7 | 37 | L | 1 | Away | Louisville | Paul Columbia | playoff at Louisville | ||||
| 2009 | 11/6 | Paul Laurence Dunbar | 28 | 13 | W | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2009 | 11/13 | Scott County | 15 | 18 | L | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2010 | 11/5 | Campbell County | 34 | 35 | L | 1 | Home | Winchester | Cardinal Stadium | Paul Columbia | playoff at Winchester | |||
| 2011 | 11/4 | Ryle | 21 | 35 | L | 1 | Away | Union | Paul Columbia | playoff at Union | ||||
| 2012 | 11/2 | Trinity | 7 | 56 | L | 1 | Away | Louisville | Steven Collins | playoff at Louisville | ||||
| 2013 | 11/8 | Scott County | 34 | 63 | L | 1 | Away | Georgetown | Toyota Stadium | Steven Collins | playoff at Georgetown | |||
| 2014 | 11/7 | Ryle | 14 | 28 | L | 1 | Away | Union | Mike Riddle | playoff at Union | ||||
| 2015 | 11/6 | Scott County | 0 | 48 | L | 1 | Away | Georgetown | Toyota Stadium | Mike Riddle | playoff at Georgetown | |||
| 2016 | 11/4 | Simon Kenton | 6 | 56 | L | 1 | Away | Independence | Chlorine B. Menefee Stadium | Oliver Lucas | playoff at Independence | |||
| 2017 | 11/3 | Scott County | 14 | 43 | L | 1 | Away | Georgetown | Toyota Stadium | Oliver Lucas | playoff at Georgetown | |||
| 2018 | 11/2 | Cooper | 21 | 48 | L | 1 | Home | Winchester | Cardinal Stadium | Oliver Lucas | playoff at Winchester | |||
| 2019 | 11/8 | Madison Central | 35 | 20 | W | 1 | Home | Winchester | Cardinal Stadium | Oliver Lucas | playoff at Winchester | |||
| 2019 | 11/15 | Oldham County | 21 | 35 | L | 1 | Home | Winchester | Cardinal Stadium | Oliver Lucas | playoff at Winchester | |||
| 2020 | 11/20 | Oldham County | 21 | 31 | L | 1 | Home | Winchester | Cardinal Stadium | Oliver Lucas | playoff at Winchester | |||
| 2021 | 11/5 | Bryan Station | 0 | 45 | L | 1 | Away | Lexington | R. L. Grider Stadium | Oliver Lucas | playoff at Lexington | |||
| 2022 | 11/4 | Tates Creek | 19 | 20 | L | 1 | Away | Lexington | Roy G. Walton Stadium | Joe Chirico | playoff at Lexington | |||
| 2023 | 11/2 | Tates Creek | 9 | 34 | L | 1 | Neutral | Lexington | R. L. Grider Stadium | Joe Chirico | playoff at Lexington | |||
| 2024 | 11/8 | Lafayette | 14 | 6 | W | 1 | Away | Lexington | James D. Ishmael Stadium | Joe Chirico | playoff at Lexington | |||
| 2024 | 11/15 | Frederick Douglass | 20 | 49 | L | 1 | Away | Lexington | Joe Chirico | playoff at Lexington | ||||
| 2025 | 11/7 | Tates Creek | 33 | 6 | W | 1 | Away | Lexington | Roy G. Walton Stadium | Joe Chirico | playoff at Lexington | |||
| 2025 | 11/14 | Madison Central | 7 | 45 | L | 1 | Home | Winchester | Cardinal Stadium | Joe Chirico | playoff at Lexington | |||
| 946 | 1,577 | 17 | 38 | 0 | .309 | |||||||||
| 17.20 | 28.67 | -11.47 |