| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes |
| 1915 | 10/8 | Christiansburg | 6 | 0 | W | 1 | Home | Salem | Roanoke College | Griffin | ||||
| 1915 | 11/12 | Christiansburg | 0 | 7 | L | 1 | Away | Christiansburg | Griffin | |||||
| 1916 | 11/10 | Christiansburg | 6 | 7 | L | 1 | Away | Christiansburg | ||||||
| 1917 | 9/28 | Christiansburg | 86 | 0 | W | 1 | Home | Salem | Northrup | |||||
| 1921 | 11/19 | Christiansburg | 41 | 0 | W | 1 | Home | Salem | Roanoke College | Pinky Spruhan | ||||
| 1922 | 11/17 | Christiansburg | 46 | 6 | W | 1 | Home | Salem | Roanoke College | L. E. Kibler | ||||
| 1923 | 11/9 | Christiansburg | 25 | 0 | W | 1 | Home | Salem | Roanoke College | L. E. Kibler | ||||
| 1924 | 10/10 | Andrew Lewis | 6 | 10 | L | 1 | Away | Salem | Roanoke College | L. E. Kibler | ||||
| 1924 | 11/11 | Christiansburg | 7 | 6 | W | 1 | Home | Salem | Roanoke College | L. E. Kibler | ||||
| 1925 | Christiansburg | 0 | 0 | T | 1 | Gordon White | ||||||||
| 1925 | 11/6 | Christiansburg | 0 | 0 | T | 1 | Away | Christiansburg | Gordon White | |||||
| 1937 | 9/25 | Christiansburg | 47 | 0 | W | 1 | Home | Salem | Municipal Stadium | Ducky Denton | ||||
| 270 | 36 | 7 | 3 | 2 | .667 | |||||||||
| 22.50 | 3.00 | 19.50 |