| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes | |
| 1966 | 9/23 | Columbus DeSales | 12 | 8 | W | 1 | Home | Cincinnati | Elder Stadium | Mike Honold | |||||
| 2009 | 10/16 | Columbus DeSales | 34 | 24 | W | 1 | Home | Cincinnati | Elder Stadium | Doug Ramsey | |||||
| 46 | 32 | 2 | 0 | 0 | 1.000 | ||||||||||
| 23.00 | 16.00 | 7.00 |