| Year | Date | Opponent | Us | Them | Result | W | L | T | OT | Where | Location | Field | Coach | Notes |
| 1920 | 10/30 | Lane Charlottesville | 20 | 0 | W | 1 | Away | Charlottesville | Leary | |||||
| 1934 | 10/27 | Lane Charlottesville | 0 | 0 | T | 1 | Home | Salem | Municipal Stadium | Ducky Denton | ||||
| 1935 | 10/25 | Lane Charlottesville | 0 | 12 | L | 1 | Away | Charlottesville | Ducky Denton | |||||
| 1936 | 10/24 | Lane Charlottesville | 7 | 0 | W | 1 | Home | Salem | Municipal Stadium | Ducky Denton | ||||
| 1937 | 10/22 | Lane Charlottesville | 2 | 0 | W | 1 | Away | Charlottesville | Ducky Denton | |||||
| 1938 | 10/23 | Lane Charlottesville | 13 | 7 | W | 1 | Home | Salem | Municipal Stadium | Ducky Denton | ||||
| 1939 | 10/13 | Lane Charlottesville | 14 | 19 | L | 1 | Away | Charlottesville | Ducky Denton | |||||
| 1940 | 10/11 | Lane Charlottesville | 33 | 0 | W | 1 | Home | Salem | Roanoke College | Ducky Denton | ||||
| 1941 | 11/1 | Lane Charlottesville | 12 | 0 | W | 1 | Away | Charlottesville | Scott Stadium | Ducky Denton | ||||
| 1942 | 10/31 | Lane Charlottesville | 0 | 7 | L | 1 | Home | Salem | Roanoke College | Charley Turner | ||||
| 1945 | 10/19 | Lane Charlottesville | 13 | 14 | L | 1 | Away | Charlottesville | Lane Field | Pinky Spruhan | ||||
| 1946 | 10/18 | Lane Charlottesville | 34 | 0 | W | 1 | Home | Salem | Municipal Stadium | Pinky Spruhan | ||||
| 1947 | 10/17 | Lane Charlottesville | 6 | 0 | W | 1 | Away | Charlottesville | Lane Field | Pinky Spruhan | ||||
| 1948 | 10/16 | Lane Charlottesville | 7 | 0 | W | 1 | Home | Salem | Municipal Stadium | Pinky Spruhan | ||||
| 1949 | 10/14 | Lane Charlottesville | 12 | 6 | W | 1 | Away | Charlottesville | Lane Field | Pinky Spruhan | ||||
| 1950 | 10/20 | Lane Charlottesville | 0 | 12 | L | 1 | Home | Salem | Municipal Stadium | Pinky Spruhan | ||||
| 1951 | 10/19 | Lane Charlottesville | 0 | 13 | L | 1 | Away | Charlottesville | Lane Field | Hal Johnston | ||||
| 1952 | 10/17 | Lane Charlottesville | 13 | 7 | W | 1 | Home | Salem | Municipal Stadium | Hal Johnston | ||||
| 1953 | 10/16 | Lane Charlottesville | 9 | 0 | W | 1 | Away | Charlottesville | Lane Field | Hal Johnston | ||||
| 1954 | 10/16 | Lane Charlottesville | 34 | 12 | W | 1 | Home | Salem | Municipal Stadium | Hal Johnston | ||||
| 1955 | 10/21 | Lane Charlottesville | 35 | 0 | W | 1 | Away | Charlottesville | Lane Field | Hal Johnston | ||||
| 1971 | 10/8 | Lane Charlottesville | 22 | 8 | W | 1 | Away | Charlottesville | Lane Field | Eddie Joyce | ||||
| 1972 | 10/13 | Lane Charlottesville | 40 | 22 | W | 1 | Home | Salem | Municipal Stadium | Eddie Joyce | ||||
| 326 | 139 | 16 | 6 | 1 | .717 | |||||||||
| 14.17 | 6.04 | 8.13 |